We are pleased to invite you to join us for the next Cardiology Grand Rounds and the Institute of CardioScience Basic Research Seminar Series, on Wednesday December 12, 2018

Dr. Monte S. Willis is a physician scientist with a research program investigating the role of protein quality control in the pathogenesis of heart failure and muscle disease and identifying biomarkers of human disease. The two major themes of their work include:

  1. Studying the role of muscle-specific ubiquitin ligases (MuRF proteins) in regulating cell signaling and metabolism
  2. Identifying the role of muscle-specific ubiquitin ligases degrade inherited mutant muscle proteins (e.g., cMyBP-C and BAG3 proteins) in the pathogenesis of heart failure

Dr. Willis is the deputy director of the Indiana Center for Musculoskeletal Health, vice chair of research in the Department of Pathology & Laboratory Medicine and is a practicing clinician overseeing the clinical chemistry laboratory and the IU School of Medicine’s clinical metabolomics program. Dr. Willis has published extensively on the use of metabolomics (both targeted and non-targeted methodologies) for basic science, translational and clinical applications, including 19 publications since 2015.

He will present during the following times:

  • 8-9 a.m. in Hurd Hall for Grand Rounds: The Role of p38 signaling in Bag3-Related Myofibrillar Cardiomyopathy.”
  •  Noon-1 p.m. in the Tilghman Auditorium on the Ground Level: Muscle‐Specific Regulation of Cardiac Autophagy and Inflammation.” Pizza will be served.

Any and all interested are welcome to come.

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