ARTICLE: A quantitative approach for measuring the reservoir of latent HIV-1 proviruses AUTHORS: Katherine M. Bruner, Zheng Wang, Francesco R. Simonetti, Alexandra M. Bender, Kyungyoon J. Kwon, Srona Sengupta, Emily J. Fray, Subul A. Beg, Annukka A. R. Antar, Katharine M. Jenike, Lynn N. Bertagnolli, Adam A. Capoferri, Joshua T. Kufera, Andrew Timmons, Christopher Nobles, John Gregg, Nikolas Wada, Ya-Chi Ho, Hao Zhang, Joseph B. Margolick, Joel N. Blankson, Steven G. Deeks, Frederic D. Bushman, Janet D. Siliciano, Gregory […]
Article of the Week
Effect of a Hospital-Initiated Program Combining Transitional Care and Long-term Self-management Support on Outcomes of Patients Hospitalized with Chronic Obstructive Pulmonary Disease: A Randomized Clinical Trial
Posted by | Article of the WeekARTICLE: Effect of a Hospital-Initiated Program Combining Transitional Care and Long-term Self-management Support on Outcomes of Patients Hospitalized with Chronic Obstructive Pulmonary Disease: A Randomized Clinical Trial AUTHORS: Hanan Aboumatar, Mohammad Naqibuddin, Suna Chung, Hina Chaudhry, Samuel W. Kim, Jamia Saunders, Lee Bone, Ayse P. Gurses, Amy Knowlton, Peter Pronovost, Nirupama Putcha, Cynthia Rand, Debra Roter, Carol Sylvester, Carol Thompson, Jennifer L. Wolff, Judith Hibbard, Robert Wise […]
Lipid Management for the Prevention of Atherosclerotic Cardiovascular Disease
Posted by | Article of the WeekARTICLE: Lipid Management for the Prevention of Atherosclerotic Cardiovascular Disease AUTHORS: Erin D. Michos, John W. McEvoy, and Roger S. Blumenthal JOURNAL: N Engl J Med. 2019 Oct 17; 381:1557-1567 In 1961, the investigators involved in the Framingham Heart Study identified serum cholesterol as one of the “factors of risk” for coronary heart disease.1 Since then, […]
Therapeutic Modulation of the Immune Response in Arrhythmogenic Cardiomyopathy
Posted by | Article of the WeekARTICLE: Therapeutic Modulation of the Immune Response in Arrhythmogenic Cardiomyopathy AUTHORS: Stephen P. Chelko, Angeliki Asimaki, Justin Lowenthal, Carlos Bueno-Beti, Djahida Bedja, Arianna Scalco, Nuria Amat-Alarcon, Peter Andersen, Daniel P. Judge, Leslie Tung, Jeffrey E. Saffitz JOURNAL: Circulation. 2019 Sep 19; 140:1491–1505. doi.org/10.1161/CIRCULATIONAHA.119.040676 Abstract Background: Inflammation is a prominent feature of arrhythmogenic cardiomyopathy (ACM), but […]
Isoniazid Preventive Therapy in HIV-Infected Pregnant and Postpartum Women
Posted by | Article of the WeekARTICLE: Isoniazid Preventive Therapy in HIV-Infected Pregnant and Postpartum Women AUTHORS: Amita Gupta, Grace Montepiedra, Lisa Aaron, Gerhard Theron, Katie McCarthy, Sarah Bradford, Tsungai Chipato, Tichaona Vhembo, Lynda Stranix-Chibanda, Carolyne Onyango-Makumbi, Gaerolwe R. Masheto, Avy Violari, et al., for the IMPAACT P1078 TB APPRISE Study Team JOURNAL: N Engl J Med. 2019 Oct 3;381(14):1333-1346. doi: 10.1056/NEJMoa1813060. Abstract BACKGROUND: The safety, efficacy, and […]
Ten Recommendations to Enhance Recruitment, Retention and Career Advancement of Women Cardiologists
Posted by | Article of the WeekARTICLE: Ten Recommendations to Enhance Recruitment, Retention and Career Advancement of Women Cardiologists AUTHORS: Garima Sharma, Amy A. Sarma, Mary Norine Walsh, Sharonne N. Hayes, Sheila Sahni, Sherry-Ann Brown, Toniya Singh, Robert A. Harrington, Pamela S. Douglas, Claire S. Duvernoy and for the American College of Cardiology Women in Cardiology Leadership Council and Diversity and Inclusion Task Force JOURNAL: JACC. 2019 Oct; 74(14). DOI: 10.1016/j.jacc.2019.08.016 Women are […]
Patient Perceptions of Diabetes Guideline Frameworks for Individualizing Glycemic Targets
Posted by | Article of the WeekARTICLE: Patient Perceptions of Diabetes Guideline Frameworks for Individualizing Glycemic Targets AUTHORS: Nancy L. Schoenborn, Norah L. Crossnohere, John F. P. Bridges, Craig E. Pollack, Scott J. Pilla and Cynthia M. Boyd JOURNAL: JAMA Intern Med. 2019 Sep 16. doi: 10.1001/jamainternmed.2019.3806. [Epub ahead of print] Abstract IMPORTANCE: Diabetes guidelines recommend considering specific factors, such as diabetes duration and life […]
Leptin Induces Hypertension Acting on Transient Receptor Potential Melastatin 7 Channel in the Carotid Body
Posted by | Article of the WeekARTICLE: Leptin Induces Hypertension Acting on Transient Receptor Potential Melastatin 7 Channel in the Carotid Body AUTHORS: Mi-Kyung Shin, Candela Caballero-Eraso, Yun-Ping Mu, Chenjuan Gu, Bonnie HY Hyeung, Lenise J Kim, Xiao-Ru Liu, Zhi-Juan Wu, Omkar Paudel, Luis E Pichard, Machiko Shirahata, Wan-Yee Tang, James S.K Sham, and Vsevolod Y Polotsky JOURNAL: Circ Res. 2019 Sep 23. […]
Therapeutic Inertia in Cardiovascular Disease Prevention
Posted by | Article of the WeekARTICLE: Therapeutic Inertia in Cardiovascular Disease Prevention AUTHORS: Dave L. Dixon, Garima Sharma, Pratik B. Sandesara, Eugene Yang, Lynne T. Braun, George A. Mensah, Laurence S. Sperling, Prakash C. Deedwania and Salim S. Virani JOURNAL: JACC. 2019 Oct;74(13). Doi: 10.1016/j.jacc.2019.08.014 The decline in cardiovascular (CV) mortality over the last 50 years can be largely attributed to advance in preventive care (1). Despite these improvements, atherosclerotic cardiovascular […]
A Professional Standard for Informed Consent for Stem Cell Therapies
Posted by | Article of the WeekARTICLE: A Professional Standard for Informed Consent for Stem Cell Therapies AUTHORS: Jeremy Sugarman, Roger A. Barker, R. Alta Charo JOURNAL: JAMA. 2019 Aug 12. doi: 10.1001/jama.2019.11290. [Epub ahead of print] In November 2018, the US Food and Drug Administration (FDA) issued a press release that stated: “The potential health benefits of regenerative medicine have spurred major progress in stem-cell […]