Article of the Week

Response to Comments on Young-Hyman et al. Psychosocial Care for People With Diabetes: A Position Statement of the American Diabetes Association

Response to Comments on Young-Hyman et al. Psychosocial Care for People With Diabetes: A Position Statement of the American Diabetes Association

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ARTICLE: Response to Comments on Young-Hyman et al. Psychosocial Care for People With Diabetes: A Position Statement of the American Diabetes Association AUTHORS: Deborah Young-Hyman, Mary de Groot, Felicia Hill-Briggs, Jeffrey Gonzalez, Korey Hood and Mark Peyrot JOURNAL: Diabetes Care. 2017 Sep;40(9):e131-e132. doi: 10.2337/dci16-0051. Thanks to Drs. Kalra, Balhara, Mezuk, Pouwer, and Campbell and Ms. Macdonald for(...)

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Safety and Tolerability of Maraviroc-Containing Regimens to Prevent HIV Infection in Women

Safety and Tolerability of Maraviroc-Containing Regimens to Prevent HIV Infection in Women

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ARTICLE: Safety and Tolerability of Maraviroc-Containing Regimens to Prevent HIV Infection in Women AUTHORS: Roy M. Gulick, Timothy J. Wilkin, Ying Q. Chen, Raphael J. Landovitz, K. Rivet Amico, Alicia M. Young, Paul Richardson, Mark A. Marzinke, Craig W. Hendrix, Susan H. Eshleman, Ian McGowan, Leslie M. Cottle, Adriana Andrade, Cheryl Marcus, Karin L. Klingman,(...)

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Nonmyocyte ERK1/2 signaling contributes to load-induced cardiomyopathy in Marfan mice

Nonmyocyte ERK1/2 signaling contributes to load-induced cardiomyopathy in Marfan mice

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ARTICLE: Nonmyocyte ERK1/2 signaling contributes to load-induced cardiomyopathy in Marfan mice. AUTHORS: Rosanne Rouf, Elena Gallo MacFarlane, Eiki Takimoto, Rahul Chaudhary, Varun Nagpal, Peter P. Rainer, Julia G. Bindman, Elizabeth E. Gerber, Djahida Bedja, Christopher Schiefer, Karen L. Miller, Guangshuo Zhu, Loretha Myers, Nuria Amat-Alarcon, Dong I. Lee, Norimichi Koitabashi, Daniel P. Judge, David A. Kass and Harry C. Dietz JOURNAL: JCI Insight. 2017 Aug 3;2(15). pii: 91588. doi: 10.1172/jci.insight.91588.(...)

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A Survey of Unregulated Direct-to-Consumer Treatment Centers Providing Stem Cells for Patients With Heart Failure

A Survey of Unregulated Direct-to-Consumer Treatment Centers Providing Stem Cells for Patients With Heart Failure

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ARTICLE: A Survey of Unregulated Direct-to-Consumer Treatment Centers Providing Stem Cells for Patients With Heart Failure AUTHORS: Zackary D. Goff, Andrew B. Kichura, John T. Chibnall, Paul J. Hauptman JOURNAL: JAMA Intern Med. 2017 Jul 24. doi: 10.1001/jamainternmed.2017.2988. [Epub ahead of print] Abstract Stem cell therapy for the treatment of heart failure (HF) is under investigation but not approved by the US(...)

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Association of History of Dizziness and Long-term Adverse Outcomes With Early vs Later Orthostatic Hypotension Assessment Times in Middle-aged Adults

Association of History of Dizziness and Long-term Adverse Outcomes With Early vs Later Orthostatic Hypotension Assessment Times in Middle-aged Adults

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ARTICLE: Association of History of Dizziness and Long-term Adverse Outcomes With Early vs Later Orthostatic Hypotension Assessment Times in Middle-aged Adults. AUTHORS: Stephen P. Juraschek, Natalie Daya, Andreea M. Rawlings, Lawrence J. Appel, Edgar R. Miller III, B. Gwen Windham, Michael E. Griswold, Gerardo Heiss, Elizabeth Selvin JOURNAL: JAMA Intern Med. 2017 Jul 24. doi: 10.1001/jamainternmed.2017.2937. [Epub ahead of print] Abstract IMPORTANCE: Guidelines recommend assessing orthostatic hypotension (OH) 3 minutes after(...)

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Nonmyocyte ERK1/2 signaling contributes to load-induced cardiomyopathy in Marfan mice

Nonmyocyte ERK1/2 signaling contributes to load-induced cardiomyopathy in Marfan mice

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ARTICLE: Nonmyocyte ERK1/2 signaling contributes to load-induced cardiomyopathy in Marfan mice AUTHORS: Rosanne Rouf, Elena Gallo MacFarlane, Eiki Takimoto, Rahul Chaudhary, Varun Nagpal, Peter P. Rainer, Julia G. Bindman, Elizabeth E. Gerber, Djahida Bedja, Christopher Schiefer, Karen L. Miller, Guangshuo Zhu, Loretha Myers, Nuria Amat-Alarcon, Dong I. Lee, Norimichi Koitabashi, Daniel P. Judge, David A. Kass and Harry C. Dietz JOURNAL: JCI Insight. 2017 Aug 3;2(15). pii: 91588. doi: 10.1172/jci.insight.91588. [Epub(...)

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Treatment with integrase inhibitor suggests a new interpretation of HIV RNA decay curves that reveals a subset of cells with slow integration

Treatment with integrase inhibitor suggests a new interpretation of HIV RNA decay curves that reveals a subset of cells with slow integration

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ARTICLE: Treatment with integrase inhibitor suggests a new interpretation of HIV RNA decay curves that reveals a subset of cells with slow integration AUTHORS: E. Fabian Cardozo, Adriana Andrade, John W. Mellors, Daniel R. Kuritzkes, Alan S. Perelson, Ruy M. Ribeiro JOURNAL: PLoS Pathog. 2017 Jul 5;13(7):e1006478. doi: 10.1371/journal.ppat.1006478. eCollection 2017 Jul. Abstract The kinetics of HIV-1 decay under treatment depends(...)

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Cardiovascular Disease Among Transgender Adults Receiving Hormone Therapy: A Narrative Review

Cardiovascular Disease Among Transgender Adults Receiving Hormone Therapy: A Narrative Review

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ARTICLE: Cardiovascular Disease Among Transgender Adults Receiving Hormone Therapy: A Narrative Review AUTHORS: Carl G. Streed Jr., Omar Harfouch, Francoise Marvel, Roger S. Blumenthal, Seth S. Martin, Monica Mukherjee JOURNAL: Ann Intern Med. 2017 Jul 25. doi: 10.7326/M17-0577. [Epub ahead of print] Abstract Recent reports estimate that 0.6% of adults in the United States, or approximately 1.4 million persons, identify(...)

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Biophysical and biomolecular determination of cellular age in humans

Biophysical and biomolecular determination of cellular age in humans

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ARTICLE: Biophysical and biomolecular determination of cellular age in humans AUTHORS: Jude M. Phillip, Pei-Hsun Wu, Daniele M. Gilkes, Wadsworth Williams, Shaun McGovern, Jena Daya, Jonathan Chen, Ivie Aifuwa, Jerry S. H. Lee, Rong Fan, Jeremy Walston, Denis Wirtz JOURNAL: Nature Biomedical Engineering. 2017 Jul 11; 10.1038 Abstract Ageing research has focused either on assessing organ- and tissue-based changes, such as lung capacity and cardiac(...)

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Trends in Use of High-Dose Vitamin D Supplements Exceeding 1000 or 4000 International Units Daily, 1999-2014

Trends in Use of High-Dose Vitamin D Supplements Exceeding 1000 or 4000 International Units Daily, 1999-2014

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ARTICLE: Trends in Use of High-Dose Vitamin D Supplements Exceeding 1000 or 4000 International Units Daily, 1999-2014 AUTHORS: Mary R. Rooney, Lisa Harnack, Erin D. Michos, Rachel P. Ogilvie, Christopher T. Sempos, Pamela L. Lutsey JOURNAL: JAMA. 2017 Jun 20;317(23):2448-2450. doi: 10.1001/jama.2017.4392. Since 2000, there has been an increase in research on possible health benefits of vitamin D. However, a 2011 Institute of Medicine (IOM; now the(...)

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