ARTICLE: Effects of the DASH Diet and Sodium Intake on Bloating: Results From the DASH-Sodium Trial AUTHORS: Allison W. Peng, Stephen P. Juraschek, Lawrence J. Appel, Edgar R. Miller III and Noel T. Mueller JOURNAL: Am J Gastroenterol. 2019 Jul;114(7):1109-1115. doi: 10.14309/ajg.0000000000000283. Abstract INTRODUCTION: Bloating is one of the most common gastrointestinal complaints. Evidence has linked(...)
Article of the Week
Cigarette Smoking, Smoking Cessation, and Long-Term Risk of 3 Major Atherosclerotic Diseases
Posted by | Article of the WeekARTICLE: Cigarette Smoking, Smoking Cessation, and Long-Term Risk of 3 Major Atherosclerotic Diseases AUTHORS: Ning Ding, Yingying Sang, Jingsha Chen, Shoshana H. Ballew, Corey A. Kalbaugh, Maya J. Salameh, Michael J. Blaha, Matthew Allison, Gerardo Heiss, Elizabeth Selvin, Josef Coresh and Kunihiro Matsushita JOURNAL: J Am Coll Cardiol. 2019 Jul 30;74(4):498-507. doi: 10.1016/j.jacc.2019.05.049. Abstract BACKGROUND: Public statements about the effect of smoking on cardiovascular disease are predominantly based on investigations(...)
A multimodality test to guide the management of patients with a pancreatic cyst
Posted by | Article of the WeekARTICLE: A multimodality test to guide the management of patients with a pancreatic cyst AUTHORS: Simeon Springer, David L. Masica, Marco Dal Molin, Christopher Douville, Christopher J. Thoburn, Bahman Afsari, Lu Li, Joshua D. Cohen, Elizabeth Thompson, Peter J. Allen, David S. Klimstra, Mark A. Schattner, C. Max Schmidt, Michele Yip-Schneider, Rachel E. Simpson, Carlos Fernandez-Del(...)
The Right and Left Hands of the State — Two Patients at Risk of Deportation
Posted by | Article of the WeekARTICLE: The Right and Left Hands of the State — Two Patients at Risk of Deportation AUTHORS: Anita Berlin, Victoria Koski-Karell, Kathleen R. Page and Sarah Polk JOURNAL: N Engl J Med. 2019 Jul 18;381(3):197-201. doi: 10.1056/NEJMp1811607. Twenty-year-old Ms. Z. presented to the emergency department (ED) of a hospital in London, anxious and hyperventilating after 4(...)
Long-acting or extended-release antiretroviral products for HIV treatment and prevention in infants, children, adolescents, and pregnant and breastfeeding women: knowledge gaps and research priorities
Posted by | Article of the WeekARTICLE: Long-acting or extended-release antiretroviral products for HIV treatment and prevention in infants, children, adolescents, and pregnant and breastfeeding women: knowledge gaps and research priorities AUTHORS: Sharon Nachman, Claire L Townsend, Elaine J Abrams, Moherndren Archary, Edmund Capparelli, Polly Clayden, Shahin Lockman, Patrick Jean-Philippe, Kenneth Mayer, Mark Mirochnick, Jane McKenzie-White, Kimberly Struble, Heather Watts and Charles Flexner JOURNAL: Lancet HIV. 2019 Jul 12. pii: S2352-3018(19)30147-X. doi: 10.1016/S2352-3018(19)30147-X. [Epub ahead of print](...)
Effects of Nutritional Supplements and Dietary Interventions on Cardiovascular Outcomes: An Umbrella Review and Evidence Map
Posted by | Article of the WeekARTICLE: Effects of Nutritional Supplements and Dietary Interventions on Cardiovascular Outcomes: An Umbrella Review and Evidence Map AUTHORS: Safi U. Khan, Muhammad U. Khan, Haris Riaz, Shahul Valavoor, Di Zhao, Lauren Vaughan, Victor Okunrintemi, Irbaz Bin Riaz, Muhammad Shahzeb Khan, Edo Kaluski, M. Hassan Murad, Michael J. Blaha, Eliseo Guallar, Erin D. Michos JOURNAL: Ann(...)
Coronary Artery Calcium Scores of Zero and Establishing the Concept of Negative Risk Factors
Posted by | Article of the WeekARTICLE: Coronary Artery Calcium Scores of Zero and Establishing the Concept of Negative Risk Factors AUTHORS: Michael J. Blaha, Ron Blankstein and Khurram Nasir JOURNAL: J Am Coll Cardiol. 2019 Jul 9;74(1):12-14. doi: 10.1016/j.jacc.2019.05.032. The term “risk factor” was first coined in 1961 in a seminal article by Kannel et al. (1) from the Framingham Heart Study. Since then, risk factors for atherosclerotic(...)
Nanoparticle diffusion in spontaneously expectorated sputum as a biophysical tool to probedisease severity in COPD
Posted by | Article of the WeekARTICLE: Nanoparticle diffusion in spontaneously expectorated sputum as a biophysical tool to probedisease severity in COPD AUTHORS: Jane F. Chisholm, Siddharth K. Shenoy, Julie K. Shade, Victor Kim, Nirupama Putcha, Kathryn A. Carson, Robert Wise, Nadia Hansel, Justin S. Hanes, Jung Soo Suk, Enid Neptune JOURNAL: Eur Respir J. 2019 Jun 4. pii: 1900088. doi: 10.1183/13993003.00088-2019. [Epub ahead of print] Abstract RATIONALE: Perturbations in airway mucus properties contribute to lung function decline in patients with chronic obstructive pulmonary disease (COPD). While alterations in bulk(...)
Self-medication as Part of Self-management Plans for Patients with COPD – Reply
Posted by | Article of the WeekARTICLE: Self-medication as Part of Self-management Plans for Patients with COPD - Reply AUTHORS: Hanan Aboumatar and Robert Wise JOURNAL: JAMA. 2019 May 21;321(19):1937. doi: 10.1001/jama.2019.2076. In Reply We agree with Dr Steurer-Stey that the use of action plans with adequate instructions for self-medication can be helpful for the management of some patients with COPD. However,(...)
A Public BCR Present in a Unique Dual-Receptor-Expressing Lymphocyte from Type 1 DiabetesPatients Encodes a Potent T Cell Autoantigen
Posted by | Article of the WeekARTICLE: A Public BCR Present in a Unique Dual-Receptor-Expressing Lymphocyte from Type 1 Diabetes Patients Encodes a Potent T Cell Autoantigen AUTHORS: Rizwan Ahmed, Zahra Omidian, Adebola Giwa, Benjamin Cornwell, Neha Majety, David R. Bell, Sangyun Lee, Hao Zhang, Aaron Michels, Stephen Desiderio, Scheherazade Sadegh-Nasseri, Hamid Rabb, Simon Gritsch, Mario L. Suva, Patrick Cahan, Ruhong Zhou, Chunfa Jie, Thomas(...)