ARTICLE: Analyzing the unperturbed HIV-1 T cell reservoir
AUTHORS: Brianna Lopez , Robert F Siliciano
JOURNAL: Trends Immunol. 2023 Mar;44(3):147-149. doi: 10.1016/j.it.2023.01.007. Epub 2023 Feb 2.
The latent reservoir for HIV-1 prevents cure but is difficult to characterize due to the low frequency of latently infected cells and the absence of unique markers. Sun et al. used single cell analysis of T cell surface phenotypes to provide evidence for immune selection of reservoir cells.
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