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Ndumele Advances Preventive Cardiology

Dr. Chiadi Ndumele, associate professor in the Division of Cardiology, has led the most important advance in Preventive Cardiology in the last decade with the recent publication of two landmark articles in Circulation.

There is a high prevalence of poor cardiovascular-kidney-metabolic health in the population, with a disproportionate burden in those with adverse social determinants of health. However, there is also a growing number of therapeutic options that target metabolic risk factors and kidney function, and these options also have cardioprotective effects. Dr. Ndumele’s AHA Presidential Advisory provides guidance on the definition, staging, prediction paradigms and approaches to care for cardiovascular-kidney-metabolic syndrome. It also sets a vision for effectively and equitably enhancing cardiovascular-kidney-metabolic health.

AHA Presidential Advisory

Cardiovascular-Kidney-Metabolic Health: A Presidential Advisory From the American Heart Association

Chiadi Ndumele et al. Circulation 2023


Cardiovascular-kidney-metabolic health reflects the interplay among metabolic risk factors, chronic kidney disease, and the cardiovascular system and has profound impacts on morbidity and mortality. There are multisystem consequences of poor cardiovascular-kidney-metabolic health...

AHA Scientific Statement

A Synopsis of the Evidence for the Science and Clinical Management of Cardiovascular-Kidney-Metabolic (CKM) Syndrome: A Scientific Statement From the American Heart Association

Chiadi Ndumele et al. Circulation 2023


A growing appreciation of the pathophysiological interrelatedness of metabolic risk factors such as obesity and diabetes, chronic kidney disease, and cardiovascular disease has led to the conceptualization of cardiovascular-kidney-metabolic syndrome. The confluence of metabolic risk factors and chronic kidney disease...


Kelsey Bennett

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