ARTICLE: Switch patterns in a cohort of individuals with asthma who received omalizumab or mepolizumab therapy
AUTHORS: Ayobami Akenroye, Tessa Ryan, Alanna McGill, Guohai Zhou, Jerome Shier, Jodi Segal
JOURNAL: J Allergy Clin Immunol Pract. 2023 Mar;11(3):946-948.e1. doi: 10.1016/j.jaip.2022.10.047. Epub 2022 Nov 13.
Clinical Implications
In individuals with elevated IgE and eosinophil count ≥150 cells/μL, approximately one-fifth of patients who initiated omalizumab and one-third who initiated mepolizumab switched over the course of follow-up. Most switches were due to effectiveness.
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