Article of the Week

MDA5 RNA-sensing pathway activation by Mycobacterium tuberculosis promotes innate immune subversion and pathogen survival

ARTICLE: MDA5 RNA-sensing pathway activation by Mycobacterium tuberculosis promotes innate immune subversion and pathogen survival AUTHORS: C Korin Bullen, Alok K Singh, Stefanie Krug, Shichun Lun, Preeti Thakur, Geetha Srikrishna, William… Read More »MDA5 RNA-sensing pathway activation by Mycobacterium tuberculosis promotes innate immune subversion and pathogen survival

ARTICLE: Analysis of the human kidney transcriptome and plasma proteome identifies markers of proximal tubule maladaptation to injury AUTHORS: Yumeng Wen, Emily Su, Leyuan Xu, Steven Menez, Dennis G… Read More »Analysis of the human kidney transcriptome and plasma proteome identifies markers of proximal tubule maladaptation to injury

ARTICLE: Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against Mycobacterium tuberculosis AUTHORS: Sadiya Parveen, Jessica Shen, Shichun Lun, Liang Zhao, Jesse Alt, Benjamin Koleske, Robert D Leone, Rana Rais, Jonathan D… Read More »Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against Mycobacterium tuberculosis

ARTICLE: Life after sickle cell disease, is it really uhuru? AUTHORS: Lydia H Pecker, Adeseye M Akinsete, C Patrick Carroll, Sophie Lanzkron, Kevin H M… Read More »Life after sickle cell disease, is it really uhuru?

ARTICLE: Biphasic decay of intact SHIV genomes following initiation of antiretroviral therapy complicates analysis of interventions targeting the reservoir AUTHORS: Mithra R Kumar, Emily J Fray, Alexandra… Read More »Biphasic decay of intact SHIV genomes following initiation of antiretroviral therapy complicates analysis of interventions targeting the reservoir

ARTICLE: Novel Imaging Approaches to Cardiac Manifestations of Systemic Inflammatory Diseases: JACC Scientific Statement AUTHORS: Brittany N Weber, Julie J Paik, Ayaz Aghayev, Allan L Klein, Sophie I Mavrogeni, Paul… Read More »Novel Imaging Approaches to Cardiac Manifestations of Systemic Inflammatory Diseases: JACC Scientific Statement

ARTICLE: Two-Week Direct-Acting Antiviral Prophylaxis for Kidney Transplantation From Donors With Hepatitis C Viremia to Recipients Without Hepatitis C Viremia: A Small Uncontrolled Trial AUTHORS:… Read More »Two-Week Direct-Acting Antiviral Prophylaxis for Kidney Transplantation From Donors With Hepatitis C Viremia to Recipients Without Hepatitis C Viremia: A Small Uncontrolled Trial

ARTICLE: Ambulatory Intensive Care for Medically Complex Patients at a Health Care Clinic for Individuals Experiencing Homelessness: The SUMMIT Randomized Clinical Trial AUTHORS: Brian Chan, Samuel… Read More »Ambulatory Intensive Care for Medically Complex Patients at a Health Care Clinic for Individuals Experiencing Homelessness: The SUMMIT Randomized Clinical Trial

ARTICLE: Efficacy and safety of avacopan in patients with ANCA-associated vasculitis receiving rituximab in a randomised trial AUTHORS: Duvuru Geetha, Anisha Dua, Huibin Yue, Jason Springer, Carlo Salvarani, David Jayne, Peter… Read More »Efficacy and safety of avacopan in patients with ANCA-associated vasculitis receiving rituximab in a randomised trial

ARTICLE: Clinical predictors of early and late endoscopic recurrence following ileocolonic resection in Crohn's disease AUTHORS: Cristian-Hernandez Rocha, Margaret Walshe, Sondra Birch, Ksenija Sabic, Ujunwa Korie, Colleen Chasteau, Vessela M Miladinova, William… Read More »Clinical predictors of early and late endoscopic recurrence following ileocolonic resection in Crohn’s disease