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Medicine Matters

Sharing successes, challenges and daily happenings in the Department of Medicine

Article of the Week

Antiretroviral therapy reveals triphasic decay of intact SIV genomes and persistence of ancestral variants

 ARTICLE: Antiretroviral therapy reveals triphasic decay of intact SIV genomes and persistence of ancestral variants AUTHORS: Emily J Fray, Fengting Wu, Francesco R Simonetti, Carolin Zitzmann, Narmada Sambaturu, Carmen Molina-Paris, Alexandra… Read More »Antiretroviral therapy reveals triphasic decay of intact SIV genomes and persistence of ancestral variants

Clonally expanded HIV-1 proviruses with 5′-leader defects can give rise to nonsuppressible residual viremia

ARTICLE: Clonally expanded HIV-1 proviruses with 5'-leader defects can give rise to nonsuppressible residual viremia AUTHORS: Jennifer A White, Fengting Wu, Saif Yasin, Milica Moskovljevic, Joseph Varriale, Filippo Dragoni, Angelica Camilo-Contreras, Jiayi… Read More »Clonally expanded HIV-1 proviruses with 5′-leader defects can give rise to nonsuppressible residual viremia

Mechanism of action of baricitinib and identification of biomarkers and key immune pathways in patients with active systemic lupus erythematosus

ARTICLE: Mechanism of action of baricitinib and identification of biomarkers and key immune pathways in patients with active systemic lupus erythematosus AUTHORS: Thomas Dörner, Yoshiya Tanaka, Ernst… Read More »Mechanism of action of baricitinib and identification of biomarkers and key immune pathways in patients with active systemic lupus erythematosus

Neutralizing activity and 3-month durability of tixagevimab and cilgavimab prophylaxis against Omicron sublineages in transplant recipients

ARTICLE: Neutralizing activity and 3-month durability of tixagevimab and cilgavimab prophylaxis against Omicron sublineages in transplant recipients AUTHORS: Andrew H Karaba, Jake D Kim, Teresa P-Y Chiang, Jennifer… Read More »Neutralizing activity and 3-month durability of tixagevimab and cilgavimab prophylaxis against Omicron sublineages in transplant recipients

Identification and Management of Atherosclerotic Cardiovascular Disease Risk in South Asian Populations in the U.S.

ARTICLE: Identification and Management of Atherosclerotic Cardiovascular Disease Risk in South Asian Populations in the U.S. AUTHORS: Anandita Agarwala, Priyanka Satish, Mahmoud Al Rifai, Anurag Mehta, Miguel Cainzos-Achirica, Nilay S.… Read More »Identification and Management of Atherosclerotic Cardiovascular Disease Risk in South Asian Populations in the U.S.

β3AR-Dependent Brain-Derived Neurotrophic Factor (BDNF) Generation Limits Chronic Postischemic Heart Failure

ARTICLE: β3AR-Dependent Brain-Derived Neurotrophic Factor (BDNF) Generation Limits Chronic Postischemic Heart Failure AUTHORS: Alessandro Cannavo, Seungho Jun, Giuseppe Rengo, Federica Marzano, Jacopo Agrimi, Daniela Liccardo, Andrea Elia, Gizem Keceli, Giovanna G Altobelli, Lorenzo Marcucci, Aram… Read More »β3AR-Dependent Brain-Derived Neurotrophic Factor (BDNF) Generation Limits Chronic Postischemic Heart Failure