Article of the Week

ARTICLE: Caring for Patients With Multiple Chronic Conditions AUTHORS: Mary E. Tinetti, Ariel R. Green, Jennifer Ouellet, Michael W. Rich, Cynthia Boyd JOURNAL: Ann Intern… Read More »Caring for Patients With Multiple Chronic Conditions

ARTICLE: Neuronal brain-region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability AUTHORS: Lindsay F. Rizzardi, Peter F. Hickey, Varenka Rodriguez DiBlasi, Rakel Tryggvadóttir, Colin M. Callahan, Adrian Idrizi, Kasper… Read More »Neuronal brain-region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability

ARTICLE: PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress AUTHORS: Mark J. Ranek, Kristen M. Kokkonen-Simon, Anna Chen, Brittany L. Dunkerly-Eyring, Miguel Pinilla Vera, Christian U. Oeing, Chirag H. Patel, Taishi Nakamura, Guangshuo Zhu, Djahida Bedja, Masayuki Sasaki, Ronald J. Holewinski, Jennifer E. Van… Read More »PKG1-modified TSC2 regulates mTORC1 activity to counter adverse cardiac stress

ARTICLE: Methylation Biomarker Panel Performance in EsophaCap Cytology Samples for Diagnosing Barrett's Esophagus: A Prospective Validation Study AUTHORS: Zhixiong Wang, Swetha Kambhampati, Yulan Cheng, Ke Ma, Cem Simsek, Alan H Tieu, John M Abraham, Xi Liu, Vishnu Prasath, Mark D Duncan, Alejandro Stark, Alexander Trick, Hua-Ling Tsai, Hao Wang, Yulong He, Mouen A Khashab, Saowanee Ngamruengphong, Eun J Shin, Tza-Huei Wang and Stephen J. Meltzer… Read More »Methylation Biomarker Panel Performance in EsophaCap Cytology Samples for Diagnosing Barrett’s Esophagus: A Prospective Validation Study

ARTICLE: Fellow Education Improved Through Mobile Clinical Decision Support Application: A Multi Center Approach Involving Peri-Procedural Antithrombotic Use AUTHORS: Alexandra T. Strauss, Theodore W. James… Read More »Fellow Education Improved Through Mobile Clinical Decision Support Application: A Multi Center Approach Involving Peri-Procedural Antithrombotic Use

ARTICLE: Substance-Use Disorders in Later Life AUTHORS: Susan W. Lehmann and Michael Fingerhood JOURNAL: NEJM. 2018 Dec 13.doi: 10.1056/NEJMra1805981 Substance-use disorders have been declared a national… Read More »Substance-Use Disorders in Later Life

ARTICLE: Rural Residence and Poverty are Independent Risk Factors for COPD in the United States AUTHORS: Sarath Raju, Corinne A Keet, Laura M Paulin, Elizabeth C Matsui, Roger D… Read More »Rural Residence and Poverty are Independent Risk Factors for COPD in the United States

ARTICLE: Pharmacotherapy of Obstructive Sleep Apnea: Is Salvation Just Around a Corner? AUTHORS: Thomaz Fleury Curado, Slava Berger and Vsevolod Y Polotsky JOURNAL: Am J Respir Crit Care… Read More »Pharmacotherapy of Obstructive Sleep Apnea: Is Salvation Just Around a Corner?

ARTICLE: Long-term remission despite clonal expansion of replication-competent HIV-1 isolates AUTHORS: Rebecca T. Veenhuis, Abena K. Kwaa, Caroline C. Garliss, Rachel Latanich, Maria Salgado, Christopher W. Pohlmeyer, Christopher L. Nobles, John Gregg, Eileen… Read More »Long-term remission despite clonal expansion of replication-competent HIV-1 isolates

ARTICLE: Trends in Mortality From Valvular Heart Disease in Europe From 2001-2015 AUTHORS: Chike C Nwabuo, Queen N Aghaji, Binu Philips, Joseph Shalhoub, Dominic Marshall… Read More »Trends in Mortality From Valvular Heart Disease in Europe From 2001-2015