Article of the Week

The iCOMPARE trial, for which Sanjay Desai is a lead investigator, examined outcomes from trainees with different duty hour standards. The trial was funded by… Read More »Assessment of Inpatient Time Allocation Among First-Year Internal Medicine Residents Using Time-Motion Observations

ARTICLE: A Genetic Risk Score Associated with COPD Susceptibility and Lung Structure on Computed Tomography AUTHORS: Elizabeth C Oelsner, Victor E Ortega, Benjamin M. Smith, Jennifer N. Nguyen, Ani… Read More »A Genetic Risk Score Associated with COPD Susceptibility and Lung Structure on Computed Tomography

ARTICLE: Fitness and 10-year risk of mortality among adults ≥70 years old at the extremes of cardiovascular disease risk factor burden: the FIT Project AUTHORS:… Read More »Fitness and 10-year risk of mortality among adults ≥70 years old at the extremes of cardiovascular disease risk factor burden: the FIT Project

ARTICLE: Selective Use of Coronary Artery Calcium Testing for Shared Decision Making: Guideline Endorsed and Ready for Prime Time AUTHORS: Rhanderson Cardoso, Khurram Nasir, Roger… Read More »Selective Use of Coronary Artery Calcium Testing for Shared Decision Making: Guideline Endorsed and Ready for Prime Time

ARTICLE: Effect of increased dose of total body irradiation on graft failure associated with HLA-haploidentical transplantation in patients with severe haemoglobinopathies: a prospective clinical trial… Read More »Effect of increased dose of total body irradiation on graft failure associated with HLA-haploidentical transplantation in patients with severe haemoglobinopathies: a prospective clinical trial

From Bench to Bedside: Animal Model Leads to Novel, 1-month TB Preventive Therapy Identification and treatment of individuals with latent tuberculosis (TB) infection to prevent… Read More »One Month of Rifapentine plus Isoniazid to Prevent HIV-Related Tuberculosis

ARTICLE: Patient Safety Outcomes under Flexible and Standard Resident Duty-Hour Rules AUTHORS: Jeffrey H. Silber, Lisa M. Bellini, Judy A. Shea, Sanjay V. Desai, David F. Dinges, Mathias Basner, Orit Even-Shoshan, Alexander S. Hill, Lauren L.… Read More »Patient Safety Outcomes Under Flexible and Standard Resident Duty-Hour Rules

ARTICLE: Human primary liver cancer organoids reveal intratumor and interpatient drug response heterogeneity AUTHORS: Ling Li*, Hildur Knutsdottir, Ken Hui*, Matthew J. Weiss, Jin He, Benjamin Philosophe, Andrew M. Cameron, Christopher L. Wolfgang, Timothy M. Pawlik, Gabriel Ghiaur, Andrew J. Ewald, Esteban… Read More »Human primary liver cancer organoids reveal intratumor and interpatient drug response heterogeneity

ARTICLE: Caring for Patients With Multiple Chronic Conditions AUTHORS: Mary E. Tinetti, Ariel R. Green, Jennifer Ouellet, Michael W. Rich, Cynthia Boyd JOURNAL: Ann Intern… Read More »Caring for Patients With Multiple Chronic Conditions

ARTICLE: Neuronal brain-region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability AUTHORS: Lindsay F. Rizzardi, Peter F. Hickey, Varenka Rodriguez DiBlasi, Rakel Tryggvadóttir, Colin M. Callahan, Adrian Idrizi, Kasper… Read More »Neuronal brain-region-specific DNA methylation and chromatin accessibility are associated with neuropsychiatric trait heritability