Article of the Week

ARTICLE: Oxidized CaMKII promotes asthma through the activation of mast cells AUTHORS: Jingjing Qu, Danh C. Do, Yufeng Zhou, Elizabeth Luczak, Wayne Mitzner, Mark E.… Read More »Oxidized CaMKII promotes asthma through the activation of mast cells

ARTICLE: Expected effects of adopting a 9 month regimen for multidrug-resistant tuberculosis: a population modelling analysis. AUTHORS: Emily A Kendall, Anthony T Fojo, David W Dowdy JOURNAL:… Read More »Expected effects of adopting a 9 month regimen for multidrug-resistant tuberculosis: a population modelling analysis

ARTICLE: Dementia and Alzheimer's Disease among Older Kidney Transplant Recipients AUTHORS: Mara A. McAdams-DeMarco, Sunjae Bae, Nadia Chu, Alden L. Gross, Charles H. Brown IV, Esther Oh, Paul Rosenberg, Karin J. Neufeld, Ravi… Read More »Dementia and Alzheimer’s Disease among Older Kidney Transplant Recipients

ARTICLE: Navigating Ethical Tensions in High-Value Care Education AUTHORS: Matthew DeCamp and Kevin R. Riggs JOURNAL: JAMA. 2016 Dec 6;316(21):2189-2190. doi: 10.1001/jama.2016.17488. Enthusiasm for high-value care is increasing throughout health… Read More »Navigating Ethical Tensions in High-Value Care Education

ARTICLE: Coronary Artery Calcium to Guide a Personalized Risk-Based Approach to Initiation and Intensification of Antihypertensive Therapy AUTHORS: John W. McEvoy, Seth S. Martin, Zeina A. Dardari, Michael D. Miedema, Veit Sandfort, Joseph Yeboah, Matthew J. Budoff, David C. Goff,Bruce M. Psaty, Wendy S. Post, Khurram Nasir, Roger S. Blumenthal, Michael… Read More »Coronary Artery Calcium to Guide a Personalized Risk-Based Approach to Initiation and Intensification of Antihypertensive Therapy

ARTICLE: Discovery and Validation of Agonistic Angiotensin Receptor Autoantibodies as Biomarkers of Adverse Outcomes AUTHORS: Peter Abadir, Alka Jain, Laura Powell, Qian-Li Xue, Jing Tian, Robert G. Hamilton, David Bennett, Thomas Finucane, Jeremy… Read More »Discovery and Validation of Agonistic Angiotensin Receptor Autoantibodies as Biomarkers of Adverse Outcomes

T cells are an important arm of the immune system that controls infections and tumor growth. When T cells fail, viruses and tumors persist and… Read More »TGFβ1-Mediated SMAD3 Enhances PD-1 Expression on Antigen-Specific T Cells in Cancer

ARTICLE: Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia AUTHORS: Zhaohui Gu, Michelle Churchman, Kathryn Roberts, Yongjin Li, Yu Liu, Richard C. Harvey, Kelly McCastlain, Shalini C. Reshmi, Debbie Payne-Turner, Ilaria Iacobucci, Ying… Read More »Genomic analyses identify recurrent MEF2D fusions in acute lymphoblastic leukaemia

ARTICLE: Glucagon-like peptide-1 receptor agonists and risk of breast cancer. AUTHORS: Shari D Bolen and Nisa M Maruthur JOURNAL: BMJ. 2016 Oct 20;355:i5519. doi: 10.1136/bmj.i5519. Although… Read More »Glucagon-like peptide-1 receptor agonists and risk of breast cancer