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Medicine Matters

Sharing successes, challenges and daily happenings in the Department of Medicine

Article of the Week

Vaccinia vaccine–based immunotherapy arrests and reverses established pulmonary fibrosis

ARTICLE: Vaccinia vaccine–based immunotherapy arrests and reverses established pulmonary fibrosis AUTHORS: Samuel L. Collins, Yee Chan-Li, MinHee Oh, Christine L. Vigeland, Nathachit Limjunyawong, Wayne Mitzner, Jonathan D. Powell and Maureen R. Horton JOURNAL: JCI Insight.… Read More »Vaccinia vaccine–based immunotherapy arrests and reverses established pulmonary fibrosis

Risk score overestimation: the impact of individual cardiovascular risk factors and preventive therapies on the performance of the American Heart Association-American College of Cardiology-Atherosclerotic Cardiovascular Disease risk score in a modern multi-ethnic cohort

ARTICLE: Risk score overestimation: the impact of individual cardiovascular risk factors and preventive therapies on the performance of the American Heart Association-American College of Cardiology-AtheroscleroticCardiovascular Disease risk score in a modern multi-ethnic cohort. AUTHORS: Andrew Paul DeFilippis, Rebekah Young, John W. McEvoy, Erin D. Michos, Veit Sandfort, Richard A. Kronmal, Robyn L. McClelland, Michael J. Blaha JOURNAL: Eur Heart J. 2016 Jul 19. pii: ehw301. [Epub ahead of… Read More »Risk score overestimation: the impact of individual cardiovascular risk factors and preventive therapies on the performance of the American Heart Association-American College of Cardiology-Atherosclerotic Cardiovascular Disease risk score in a modern multi-ethnic cohort

Phenotype-Specific Treatment of Heart Failure With Preserved Ejection Fraction: A Multiorgan Roadmap

ARTICLE: Phenotype-Specific Treatment of Heart Failure With Preserved Ejection Fraction: A Multiorgan Roadmap AUTHORS: Sanjiv J. Shah, Dalane W. Kitzman, Barry A. Borlaug, Loek van Heerebeek, Michael R. Zile, David A. Kass and Walter J. Paulus JOURNAL: Circulation. 2016 Jul 5;134(1):73-90. doi: 10.1161/CIRCULATIONAHA.116.021884.… Read More »Phenotype-Specific Treatment of Heart Failure With Preserved Ejection Fraction: A Multiorgan Roadmap

Trans-ethnic Meta Analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucoseand Insulin

ARTICLE: Trans-ethnic Meta Analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucoseand Insulin AUTHORS: Ching-Ti Liu, Sridharan Raghavan, Nisa Maruthur, Edmond Kato Kabagambe, Jaeyoung Hong, Maggie C.Y. Ng, Marie-France Hivert, Yingchang Lu, Ping An, Amy R. Bentley, Anne M. Drolet,… Read More »Trans-ethnic Meta Analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucoseand Insulin

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

ARTICLE: A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease AUTHORS: Robert A. Scott, Daniel F. Freitag,… Read More »A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease