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Medicine Matters

Sharing successes, challenges and daily happenings in the Department of Medicine

Impact of recipient age on mortality among Cytomegalovirus (CMV)-seronegative lung transplant recipients with CMV-seropositive donors

ARTICLE: Impact of recipient age on mortality among Cytomegalovirus (CMV)-seronegative lung transplant recipients with CMV-seropositive donors AUTHORS: Sara Belga, Sarah Hussain, Robin K Avery, Zeba Nauroz, Christine M Durand, Elizabeth… Read More »Impact of recipient age on mortality among Cytomegalovirus (CMV)-seronegative lung transplant recipients with CMV-seropositive donors

Neutralizing antibodies evolve to exploit vulnerable sites in the HCV envelope glycoprotein E2 and mediate spontaneous clearance of infection

ARTICLE: Neutralizing antibodies evolve to exploit vulnerable sites in the HCV envelope glycoprotein E2 and mediate spontaneous clearance of infection AUTHORS: Nicole Frumento, Ariadne Sinnis-Bourozikas, Harry T… Read More »Neutralizing antibodies evolve to exploit vulnerable sites in the HCV envelope glycoprotein E2 and mediate spontaneous clearance of infection

Baricitinib for systemic lupus erythematosus: a double-blind, randomised, placebo-controlled, phase 3 trial (SLE-BRAVE-II)

ARTICLE: Baricitinib for systemic lupus erythematosus: a double-blind, randomised, placebo-controlled, phase 3 trial (SLE-BRAVE-II) AUTHORS: Michelle Petri, Ian N Bruce, Thomas Dörner, Yoshiya Tanaka, Eric… Read More »Baricitinib for systemic lupus erythematosus: a double-blind, randomised, placebo-controlled, phase 3 trial (SLE-BRAVE-II)

Proviral location affects cognate peptide-induced virus production and immune recognition of HIV-1-infected T cell clones

ARTICLE: Proviral location affects cognate peptide-induced virus production and immune recognition of HIV-1-infected T cell clones AUTHORS: Filippo Dragoni, Abena K Kwaa, Caroline C Traut, Rebecca T Veenhuis, Bezawit… Read More »Proviral location affects cognate peptide-induced virus production and immune recognition of HIV-1-infected T cell clones

MDA5 RNA-sensing pathway activation by Mycobacterium tuberculosis promotes innate immune subversion and pathogen survival

ARTICLE: MDA5 RNA-sensing pathway activation by Mycobacterium tuberculosis promotes innate immune subversion and pathogen survival AUTHORS: C Korin Bullen, Alok K Singh, Stefanie Krug, Shichun Lun, Preeti Thakur, Geetha Srikrishna, William… Read More »MDA5 RNA-sensing pathway activation by Mycobacterium tuberculosis promotes innate immune subversion and pathogen survival