Peter Abadir (pictured), Mahya Faghih, Diep Vuong, Neal Fedarko and Jeremy Walston (pictured) recently published a paper in the Journal of Investigative Dermatology detailing preclinical studies in diabetic mouse models and diabetic aging pig models that demonstrate significantly accelerated healing in chronic wounds treated with reformulated gel made from blood pressure pills. In the pig studies, all 5 cm treatment wounds were completely closed at 56 days while none of the control treated wounds were closed. Treated wounds also exhibited significantly thicker skin layers on histological assessment (Epithelial and dermis) and significantly stronger skin by tensile strength assessment.
For the full article, visit: http://www.sciencedirect.com/science/article/pii/S0022202X17330361?via%3Dihub
Related articles:
- https://www.hopkinsmedicine.org/news/media/releases/topical_gel_made_from_oral_blood_pressure_drugs_shown_effective_in_healing_chronic_wounds_in_test_animals
- https://www.news-medical.net/news/20171101/Topical-gel-made-from-blood-pressure-pills-holds-great-promise-in-healing-chronic-wounds.aspx
- https://www.sciencedaily.com/releases/2017/11/171101102654.htm
- http://www.futurity.org/chronic-skin-wounds-valsartan-1593062-2/
- https://www.mdlinx.com/nurse-practitioner/?article_alert=1225&alert_type=lfc
- https://spinonews.com/2017/11/02/a-topical-gel-made-from-blood-pressure-drugs-controls-the-healing-of-chronic-skin-wounds/