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Sharing successes, challenges and daily happenings in the Department of Medicine

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MDA5 RNA-sensing pathway activation by Mycobacterium tuberculosis promotes innate immune subversion and pathogen survival

ARTICLE: MDA5 RNA-sensing pathway activation by Mycobacterium tuberculosis promotes innate immune subversion and pathogen survival AUTHORS: C Korin Bullen, Alok K Singh, Stefanie Krug, Shichun Lun, Preeti Thakur, Geetha Srikrishna, William… Read More »MDA5 RNA-sensing pathway activation by Mycobacterium tuberculosis promotes innate immune subversion and pathogen survival

Analysis of the human kidney transcriptome and plasma proteome identifies markers of proximal tubule maladaptation to injury

ARTICLE: Analysis of the human kidney transcriptome and plasma proteome identifies markers of proximal tubule maladaptation to injury AUTHORS: Yumeng Wen, Emily Su, Leyuan Xu, Steven Menez, Dennis G… Read More »Analysis of the human kidney transcriptome and plasma proteome identifies markers of proximal tubule maladaptation to injury

Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against Mycobacterium tuberculosis

ARTICLE: Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against Mycobacterium tuberculosis AUTHORS: Sadiya Parveen, Jessica Shen, Shichun Lun, Liang Zhao, Jesse Alt, Benjamin Koleske, Robert D Leone, Rana Rais, Jonathan D… Read More »Glutamine metabolism inhibition has dual immunomodulatory and antibacterial activities against Mycobacterium tuberculosis

Biphasic decay of intact SHIV genomes following initiation of antiretroviral therapy complicates analysis of interventions targeting the reservoir

ARTICLE: Biphasic decay of intact SHIV genomes following initiation of antiretroviral therapy complicates analysis of interventions targeting the reservoir AUTHORS: Mithra R Kumar, Emily J Fray, Alexandra… Read More »Biphasic decay of intact SHIV genomes following initiation of antiretroviral therapy complicates analysis of interventions targeting the reservoir