ARTICLE: Interventions to Address Medical Conditions and Health-Risk Behaviors Among Persons With Serious Mental Illness: A Comprehensive Review AUTHORS: Emma E. McGinty, Julia Baller, Susan T. Azrin, Denise Juliano-Bult, Gail L. Daumit JOURNAL: Schizophr Bull. 2015 Jul 28. pii: sbv101. [Epub ahead of print] Abstract People with serious mental illness (SMI) have mortality rates 2(...)
Article of the Week
Through a Gender Lens: A View of Gender and Leadership Positions in a Department of Medicine
Posted by | Article of the WeekARTICLE: Through a Gender Lens: A View of Gender and Leadership Positions in a Department of Medicine AUTHORS: Anne K. Monroe, Rachel B. Levine, Jeanne M. Clark, Janet Bickel, Susan M. MacDonald and Linda Resar JOURNAL: J Womens Health (Larchmt). 2015 Jul 22. [Epub ahead of print] Abstract BACKGROUND: Despite increasing numbers in academic medicine,(...)
Jump Forward to Get Back to Basics
Posted by | Article of the WeekARTICLE: Jump Forward to Get Back to Basics AUTHOR: Eric B. Bass JOURNAL: J Gen Intern Med. 2015 Jun 30. [Epub ahead of print] How should primary care providers react to the study by Sutkowi-Hemstreet et al. showing that many patients do not understand the benefits and harms of “overused” screening tests?1 My instinctual reaction(...)
Risk of community-acquired pneumonia with outpatient proton-pump inhibitor therapy: a systematic review and meta-analysis
Posted by | Article of the WeekARTICLE: Risk of community-acquired pneumonia with outpatient proton-pump inhibitor therapy: a systematic review and meta-analysis AUTHORS: Allison A. Lambert, Jennifer O. Lam, Julie J. Paik, Cesar Ugarte-Gil, M. Bradley Drummond, Trevor A. Crowell JOURNAL: PLoS One. 2015 Jun 4;10(6):e0128004. doi: 10.1371/journal.pone.0128004. eCollection 2015. Abstract BACKGROUND: Proton-pump inhibitors (PPIs) are among the most frequently prescribed medications.(...)
Citrullination of myofilament proteins in heart failure
Posted by | Article of the WeekARTICLE: Citrullination of myofilament proteins in heart failure AUTHORS: J. Fert-Bober, J.T. Giles, R.J. Holewinski, J.A. Kirk, H. Uhrigshardt, E.L. Crowgey, F. Andrade, C.O. Bingham 3rd, J.K. Park, M.K. Halushka, D.A. Kass, J.M. Bathon and J.E. Van Eyk JOURNAL: Cardiovasc Res. 2015 Jun 25. pii: cvv185. [Epub ahead of print] Abstract AIM: Citrullination, the post-translational(...)
Removal of Abnormal Myofilament O-GlcNAcylation Restores Ca2+ Sensitivity in Diabetic Cardiac Muscle
Posted by | Article of the WeekARTICLE: Removal of Abnormal Myofilament O-GlcNAcylation Restores Ca2+ Sensitivity in Diabetic Cardiac Muscle AUTHORS: Genaro A. Ramirez-Correa, Junfeng Ma, Chad Slawson, Quira Zeidan, Nahyr S. Lugo-Fagundo, Mingguo Xu, Xiaoxu Shen, Wei Dong Gao, Viviane Caceres, Khalid Chakir, Lauren DeVine, Robert Cole, Luigi Marchionni, Nazareno Paolocci, Gerald W. Hart and Anne M. Murphy JOURNAL: Diabetes. 2015 Jun(...)
Vinculin network-mediated cytoskeletal remodeling regulates contractile function in the aging heart
Posted by | Article of the WeekARTICLE: Vinculin network-mediated cytoskeletal remodeling regulates contractile function in the aging heart AUTHORS: Gaurav Kaushik, Alice Spenlehauer, Ayla O. Sessions, Adriana S. Trujillo, Alexander Fuhrmann, Zongming Fu, Vidya Venkatraman, Danielle Pohl, Jeremy Tuler, Mingyi Wang, Edward G. Lakatta, Karen Ocorr, Rolf Bodmer, Sanford I. Bernstein, Jennifer E. Van Eyk, Anthony Cammarato and Adam J. Engler(...)
Introduction to a compendium on sudden cardiac death: epidemiology, mechanisms and management
Posted by | Article of the WeekARTICLE: Introduction to a compendium on sudden cardiac death: epidemiology, mechanisms and management AUTHOR: Gordon F. Tomaselli JOURNAL: Circulation Research. June 5, 2015; Vol. 116, No. 12 Overview of Sudden Cardiac Death and Scope of the Compendium Sudden cardiac death (SCD) is a devastating complication of many forms of heart disease and on occasion presents(...)
Atypical HUS may become a diagnosis of inclusion
Posted by | Article of the WeekARTICLE: Atypical HUS may become a diagnosis of inclusion AUTHORS: J. Evan Sadler JOURNAL: Blood. 2015 Jun 4;125(23):3525-6. doi: 10.1182/blood-2015-04-640656 Patients with aHUS usually have microangiopathic hemolytic anemia, thrombocytopenia, and renal failure. However, these features occur in many diseases, including thrombotic thrombocytopenic purpura (TTP), and the more common form of Shiga toxin–expressing Escherichia coli hemolytic(...)
Phosphorus-32, a Clinically Available Drug, Inhibits Cancer Growth by Inducing DNA Double-Strand Breakage
Posted by | Article of the WeekARTICLE: Phosphorus-32, a Clinically Available Drug, Inhibits Cancer Growth by Inducing DNA Double-Strand Breakage AUTHOURS: Yulan Cheng, Ana P. Kiess, Joseph M. Herman, Martin G. Pomper, Stephen J. Meltzer, John M. Abraham JOURNAL: PLoS One. 2015 Jun 1;10(6):e0128152. doi: 10.1371/journal.pone.0128152. eCollection 2015. Abstract Radioisotopes that emit electrons (beta particles), such as radioiodine, can effectively kill(...)