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Sharing successes, challenges and daily happenings in the Department of Medicine

Article of the Week

HIF-1 Interacts with TRIM28 and DNA-PK to release paused RNA polymerase II and activate target gene transcription in response to hypoxia

ARTICLE: HIF-1 Interacts with TRIM28 and DNA-PK to release paused RNA polymerase II and activate target gene transcription in response to hypoxia AUTHORS: Yongkang Yang, Haiquan… Read More »HIF-1 Interacts with TRIM28 and DNA-PK to release paused RNA polymerase II and activate target gene transcription in response to hypoxia

Deprescribing Education vs Usual Care for Patients With Cognitive Impairment and Primary Care Clinicians: The OPTIMIZE Pragmatic Cluster Randomized Trial

ARTICLE: Deprescribing Education vs Usual Care for Patients With Cognitive Impairment and Primary Care Clinicians: The OPTIMIZE Pragmatic Cluster Randomized Trial AUTHORS: Elizabeth A Bayliss,… Read More »Deprescribing Education vs Usual Care for Patients With Cognitive Impairment and Primary Care Clinicians: The OPTIMIZE Pragmatic Cluster Randomized Trial

Isolated Diastolic Hypertension and Risk of Cardiovascular Disease: Controversies in Hypertension—Con Side of the Argument

ARTICLE: Isolated Diastolic Hypertension and Risk of Cardiovascular Disease: Controversies in Hypertension—Con Side of the Argument AUTHORS: Alan P Jacobsen, Myles McKittrick, Natalie Daya, Mahmoud Al Rifai, John W… Read More »Isolated Diastolic Hypertension and Risk of Cardiovascular Disease: Controversies in Hypertension—Con Side of the Argument

Myocardial ATP depletion detected noninvasively predicts sudden cardiac death risk in patients with heart failure

ARTICLE: Myocardial ATP depletion detected noninvasively predicts sudden cardiac death risk in patients with heart failure AUTHORS: T Jake Samuel, Shenghan Lai, Michael Schär, Katherine C Wu, Angela M… Read More »Myocardial ATP depletion detected noninvasively predicts sudden cardiac death risk in patients with heart failure