Article of the Week

Converging genetic and epigenetic drivers of paediatric acute lymphoblastic leukaemia identified by an information-theoretic analysis

ARTICLE: Converging genetic and epigenetic drivers of paediatric acute lymphoblastic leukaemia identified by an information-theoretic analysis AUTHORS: Michael A. Koldobskiy, Garrett Jenkinson, Jordi Abante, Varenka A. Rodriguez DiBlasi, Weiqiang… Read More »Converging genetic and epigenetic drivers of paediatric acute lymphoblastic leukaemia identified by an information-theoretic analysis

ARTICLE: MCU Overexpression Rescues Inotropy and Reverses Heart Failure by Reducing SR Ca2+ Leak AUTHORS: Ting Liu, Ni Yang, Agnieszka Sidor, Brian O’Rourke JOURNAL: Circ Res. 2021 Apr 16;128(8):1191-1204. doi: 10.1161/CIRCRESAHA.120.318562. Epub… Read More »MCU Overexpression Rescues Inotropy and Reverses Heart Failure by Reducing SR Ca2+ Leak

AUTHORS: Lawrence J Appel, Erin D Michos, Christine M Mitchell, Amanda L Blackford, Alice L Sternberg, Edgar R Miller 3rd, Stephen P Juraschek, Jennifer A Schrack, Sarah L Szanton, Jeanne Charleston, Melissa Minotti, Sheriza N Baksh, Robert… Read More »The Effects of Four Doses of Vitamin D Supplements on Falls in Older Adults : A Response-Adaptive, Randomized Clinical Trial

ARTICLE: Myocardial Injury in Severe COVID-19 Compared With Non-COVID-19 Acute Respiratory Distress Syndrome AUTHORS: Thomas S Metkus, Lori J Sokoll, Andreas S Barth, Matthew J Czarny, Allison G Hays,… Read More »Myocardial Injury in Severe COVID-19 Compared With Non-COVID-19 Acute Respiratory Distress Syndrome

ARTICLE: Operational Recommendations for Scarce Resource Allocation in a Public Health Crisis AUTHORS: Michael R Ehmann, Elizabeth K Zink, Amanda B Levin, Jose I Suarez, Harolyn M E Belcher, Elizabeth… Read More »Operational Recommendations for Scarce Resource Allocation in a Public Health Crisis

ARTICLE: PGC1/PPAR drive cardiomyocyte maturation at single cell level via YAP1 and SF3B2 AUTHORS: Sean A Murphy, Matthew Miyamoto, Anaïs Kervadec, Suraj Kannan, Emmanouil Tampakakis, Sandeep Kambhampati, Brian Leei Lin, Sam Paek, Peter… Read More »PGC1/PPAR drive cardiomyocyte maturation at single cell level via YAP1 and SF3B2

ARTICLE: Dolutegravir-based Antiretroviral Therapy for Patients Coinfected With Tuberculosis and Human Immunodeficiency Virus: A Multicenter, Noncomparative, Open-label, Randomized Trial AUTHORS: Kelly E Dooley, Richard Kaplan, Noluthando Mwelase, Beatriz… Read More »Dolutegravir-based Antiretroviral Therapy for Patients Coinfected With Tuberculosis and Human Immunodeficiency Virus: A Multicenter, Noncomparative, Open-label, Randomized Trial

ARTICLE: Go Red for Women Strategically Focused Research Network: Summary of Findings and Network Outcomes AUTHORS: Marie-Pierre St-Onge, Brooke Aggarwal, Matthew A Allison, Jeffrey S Berger, Sheila F Castañeda, Janet… Read More »Go Red for Women Strategically Focused Research Network: Summary of Findings and Network Outcomes

ARTICLE: Four-Week Direct-Acting Antiviral Prophylaxis for Kidney Transplantation From Hepatitis C-Viremic Donors to Hepatitis C-Negative Recipients: An Open-Label Nonrandomized Study AUTHORS: Christine M Durand, Brittany Barnaba, Sile… Read More »Four-Week Direct-Acting Antiviral Prophylaxis for Kidney Transplantation From Hepatitis C-Viremic Donors to Hepatitis C-Negative Recipients: An Open-Label Nonrandomized Study

ARTICLE: Once-weekly rifapentine and isoniazid for tuberculosis prevention in patients with HIV taking dolutegravir-based antiretroviral therapy: a phase 1/2 trial AUTHORS: Kelly E Dooley, Radojkam Savic, Akshay… Read More »Once-weekly rifapentine and isoniazid for tuberculosis prevention in patients with HIV taking dolutegravir-based antiretroviral therapy: a phase 1/2 trial