Article of the Week

Effect of CPAP on Airways Reactivity in Asthma: A Randomized Sham-Controlled Clinical Trial

Effect of CPAP on Airways Reactivity in Asthma: A Randomized Sham-Controlled Clinical Trial

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ARTICLE: Effect of CPAP on Airways Reactivity in Asthma: A Randomized Sham-Controlled Clinical Trial AUTHORS: Janet T Holbrook, Elizabeth A Sugar, Robert H Brown, Lea T Drye, Charles G. Irvin, Alan R Schwartz, Robert S Tepper, Robert A Wise, Razan Z Yasin, Michael F Busk, and on behalf of the American Lung Association–Airways Clinical Research Centers JOURNAL: Ann Am Thorac Soc. 2016 Jul 11. [Epub ahead(...)

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Office Visits Prior to Screening Colonoscopy-Reply.

Office Visits Prior to Screening Colonoscopy-Reply.

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ARTICLE: Office Visits Prior to Screening Colonoscopy-Reply. AUTHORS: Kevin R. Riggs, Eun Ji Shin, Jodi B. Segal JOURNAL: JAMA. 2016 Jun 28;315(24):2734-2735. doi: 10.1001/jama.2016.4298. In Reply to: http://jama.jamanetwork.com/article.aspx?articleid=2530523 Dr. Leow and colleagues raise several important considerations. We agree that the primary finding of our study—that among patients aged 50 to 64 years with private health insurance, nearly 30% who underwent(...)

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Trans-ethnic Meta Analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucoseand Insulin

Trans-ethnic Meta Analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucoseand Insulin

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ARTICLE: Trans-ethnic Meta Analysis and Functional Annotation Illuminates the Genetic Architecture of Fasting Glucoseand Insulin AUTHORS: Ching-Ti Liu, Sridharan Raghavan, Nisa Maruthur, Edmond Kato Kabagambe, Jaeyoung Hong, Maggie C.Y. Ng, Marie-France Hivert, Yingchang Lu, Ping An, Amy R. Bentley, Anne M. Drolet, Kyle J. Gaulton, Xiuqing Guo, Loren L. Armstrong, Marguerite R. Irvin, Man Li, Leonard Lipovich, Denis V. Rybin, Kent D. Taylor, Charles Agyemang, Nicholette D. Palmer, Brian E. Cade, Wei-Min Chen, Marco Dauriz, Joseph A.C. Delaney, Todd L. Edwards,(...)

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Inflammatory arthritis and sicca syndrome induced by nivolumab and ipilimumab

Inflammatory arthritis and sicca syndrome induced by nivolumab and ipilimumab

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ARTICLE: Inflammatory arthritis and sicca syndrome induced by nivolumab and ipilimumab AUTHORS: Laura C. Cappelli, Ana Kristina Gutierrez, Alan N. Baer, Jemima Albayda, Rebecca L. Manno, Uzma Haque, Evan J. Lipson, Karen B. Belch, Ami A. Shah, Jarushka Naidoo, Julie R. Brahmer, Dung Le, Clifton O. Bingham III JOURNAL: Ann Rheum Dis. 2016 Jun 15. pii:(...)

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Reengineering the Physical Examination for the New Millennium?

Reengineering the Physical Examination for the New Millennium?

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ARTICLE: Reengineering the Physical Examination for the New Millennium? AUTHORS: William G. Nelson, Antony Rosen, Peter J. Pronovost JOURNAL: JAMA. 2016;315(22):2391-2392. doi:10.1001/jama.2016.4470. Most patients hope for more face-to-face time with their physicians. Most physicians want to ensure that (1) a diagnosis, treatment plan, and the expected benefits or adverse effects of treatment are well understood by the patient; (2) the patient(...)

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A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease

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ARTICLE: A genomic approach to therapeutic target validation identifies a glucose-lowering GLP1R variant protective for coronary heart disease AUTHORS: Robert A. Scott, Daniel F. Freitag, Li Li, Audrey Y. Chu, Praveen Surendran, Robin Young, Niels Grarup, Alena Stancáková, Yuning Chen, Tibor V. Varga, Hanieh Yaghootkar, Jian’an Luan, Jing Hua Zhao, Sara M. Willems, Jennifer Wessel, Shuai(...)

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Right Ventricular Functional Reserve in Pulmonary Arterial Hypertension

Right Ventricular Functional Reserve in Pulmonary Arterial Hypertension

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ARTICLE: Right Ventricular Functional Reserve in Pulmonary Arterial Hypertension AUTHORS: Steven Hsu, Brian A. Houston, Emmanouil Tampakakis, Anita C. Bacher, Parker S. Rhodes, Stephen C. Mathai, Rachel L. Damico, Todd M. Kolb, Laura K. Hummers, Ami A. Shah, Zsuzsanna McMahan, Celia P. Corona-Villalobos, Stefan L. Zimmerman, Fredrick M. Wigley, Paul M. Hassoun, David A. Kass,(...)

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Low High-Density Lipoprotein Cholesterol and Incident Coronary Heart Among Blacks in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study

Low High-Density Lipoprotein Cholesterol and Incident Coronary Heart Among Blacks in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study

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ARTICLE: Low High-Density Lipoprotein Cholesterol and Incident Coronary Heart Among Blacks in the Reasons for Geographic and Racial Differences in Stroke (REGARDS) Study AUTHORS: Lisandro Colantonio, Sergio Fazio, Robert Rosenson, Michael Miller, Maciej Banach, Monika Safford, Paul Muntner, Peter Toth JOURNAL: J Am Coll Cardiol. 2016;67(13_S):1837-1837. doi:10.1016/S0735-1097(16)31838-1 Abstract Background: Low high-density lipoprotein cholesterol (HDL-C) has been(...)

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Understanding the impact of second-hand smoke exposure on clinical outcomes in participants with COPD in the SPIROMICS cohort

Understanding the impact of second-hand smoke exposure on clinical outcomes in participants with COPD in the SPIROMICS cohort

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ARTICLE: Understanding the impact of second-hand smoke exposure on clinical outcomes in participants with COPD in the SPIROMICS cohort AUTHORS: Nirupama Putcha, R Graham Barr, Meilan K Han, Prescott G Woodruff, Eugene R Bleecker, Richard E Kanner, Fernando J Martinez, Benjamin M Smith, Donald P Tashkin, Russell P Bowler, Mark D Eisner, Stephen I Rennard, Robert A Wise, Nadia N Hansel, for the SPIROMICS Investigators JOURNAL: Thorax. 2016 Mar 9. pii: thoraxjnl-2015-207487.(...)

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Changes in Food-Specific IgE Over Time in the National Health and Nutrition Examination Survey (NHANES)

Changes in Food-Specific IgE Over Time in the National Health and Nutrition Examination Survey (NHANES)

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ARTICLE: Changes in Food-Specific IgE Over Time in the National Health and Nutrition Examination Survey (NHANES) AUTHORS: Emily C. McGowan, Roger D. Peng, Päivi M. Salo, Darryl C. Zeldin, Corinne A. Keet JOURNAL: J Allergy Clin Immunol Pract. 2016 Apr 22. pii: S2213-2198(16)30011-3. doi: 10.1016/j.jaip.2016.01.017. [Epub ahead of print] Abstract Background: Food allergy prevalence appears to(...)

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