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Medicine Matters

Sharing successes, challenges and daily happenings in the Department of Medicine

Inhibition of host PARP1 contributes to the anti-inflammatory and antitubercular activity of pyrazinamide

ARTICLE: Inhibition of host PARP1 contributes to the anti-inflammatory and antitubercular activity of pyrazinamide AUTHORS: Stefanie Krug, Manish Gupta, Pankaj Kumar, Laine Feller, Elizabeth A Ihms, Bong Gu Kang, Geetha Srikrishna, Ted… Read More »Inhibition of host PARP1 contributes to the anti-inflammatory and antitubercular activity of pyrazinamide

Early Microbiologic Markers of Pulmonary Tuberculosis Treatment Outcomes

ARTICLE: Early Microbiologic Markers of Pulmonary Tuberculosis Treatment Outcomes AUTHORS: Mandar Sudhir Paradkar, Neeta Nitin Pradhan, Subramanyam Balaji, Sanjay Narayan Gaikwad, Amol Chavan, Sujata Nagnath Dharmashale, Tushar Sahasrabudhe, Rahul Lokhande, Sona Anil Deshmukh, Madhusudan… Read More »Early Microbiologic Markers of Pulmonary Tuberculosis Treatment Outcomes

Impact of recipient age on mortality among Cytomegalovirus (CMV)-seronegative lung transplant recipients with CMV-seropositive donors

ARTICLE: Impact of recipient age on mortality among Cytomegalovirus (CMV)-seronegative lung transplant recipients with CMV-seropositive donors AUTHORS: Sara Belga, Sarah Hussain, Robin K Avery, Zeba Nauroz, Christine M Durand, Elizabeth… Read More »Impact of recipient age on mortality among Cytomegalovirus (CMV)-seronegative lung transplant recipients with CMV-seropositive donors

Neutralizing antibodies evolve to exploit vulnerable sites in the HCV envelope glycoprotein E2 and mediate spontaneous clearance of infection

ARTICLE: Neutralizing antibodies evolve to exploit vulnerable sites in the HCV envelope glycoprotein E2 and mediate spontaneous clearance of infection AUTHORS: Nicole Frumento, Ariadne Sinnis-Bourozikas, Harry T… Read More »Neutralizing antibodies evolve to exploit vulnerable sites in the HCV envelope glycoprotein E2 and mediate spontaneous clearance of infection