ARTICLE: Bruton’s tyrosine kinase inhibition effectively protects against human IgE-mediated anaphylaxis AUTHORS: Melanie C Dispenza, Rebecca A Krier-Burris, Krishan D Chhiba, Bradley J Undem, Piper A Robida, Bruce S Bochner JOURNAL: J Clin Invest. 2020 Sep 1;130(9):4759-4770. doi: 10.1172/JCI138448. Abstract No known therapies can prevent anaphylaxis. Bruton's tyrosine kinase (BTK) is an enzyme thought to be essential for high-affinity IgE receptor […]
Hanst Named Grants & Contracts Administrator
Posted by | Administration, Congratulations, Leadership, ResearchAfter conducting a national recruitment, we are thrilled to announce that Becky Hanst, MS, MBA has been selected to be the Grants & Contracts Administrator for the Department of Medicine effective October 16, 2020. Her past experience and vision to lead the DOM sponsored team makes us certain she is the right person for the […]
Expanding Article of the Week to Articles of the Week
Posted by | Article of the Week, ResearchBeginning this week, we will expand the number of papers we feature every week for Article of the Week. I think there are many benefits of sharing the research findings of our hard-working researchers—such as giving investigative teams the accolades they deserve, inspiring collaboration and review between labs and divisions and encouraging more impactful research. […]
TNNT2 mutations in the tropomyosin binding region of TNT1 disrupt its role in contractile inhibition and stimulate cardiac dysfunction
Posted by | Article of the WeekARTICLE: TNNT2 mutations in the tropomyosin binding region of TNT1 disrupt its role in contractile inhibition and stimulate cardiac dysfunction AUTHORS: Aditi Madan, Meera C Viswanathan, Kathleen C Woulfe, William Schmidt, Agnes Sidor, Ting Liu, Tran H Nguyen, Bosco Trinh, Cortney Wilson, Sineej Madathil, Georg Vogler, Brian O'Rourke, Brandon J Biesiadecki, Larry S Tobacman, Anthony Cammarato JOURNAL: Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18822-18831. doi: 10.1073/pnas.2001692117. Epub 2020 Jul […]
Exercise intolerance and rapid skeletal muscle energetic decline in human age-associated frailty
Posted by | Article of the WeekARTICLE: Exercise intolerance and rapid skeletal muscle energetic decline in human age-associated frailty AUTHORS: Sabra C. Lewsey, Kilian Weiss, Michael Schär, Yi Zhang, Paul A. Bottomley,3 T. Jake Samuel, Qian-Li Xue, Angela Steinberg, Jeremy Walston, Gary Gerstenblith, and Robert G. Weiss JOURNAL: JCI Insight. 2020 Sep 17;141246. doi: 10.1172/jci.insight.141246. Online ahead of print. Abstract Background: Physical frailty in older individuals is characterized by subjective […]
Garibaldi Treats President Trump
Posted by | Congratulations, Patient CareDr. Brian Garibaldi, associate professor in the Division of Pulmonary, appeared on the news this past weekend, speaking as one of the physicians in charge of caring for President Donald Trump, who tested positive for COVID-19 last week. Dr. Garibaldi, director of the Johns Hopkins Biocontainment Unit, was consulted by the White House and Walter […]
Epic Tip of the Week: October 2, 2020
Posted by | Patient CareQuarterly Epic Upgrade: October 3, 2020 Inpatient & Ambulatory: Rover version 9.4 Enterprise Changes Check for the version number at the bottom of the login window. Review the Cross-App Rover Upgrade vMay 2020 PPT for more information. Inpatient & Ambulatory: Update Haiku / Canto to version 9.3 Haiku /Canto version 9.3 or later is required […]
KL2 Mentored Career Development Awards
Posted by | ResearchThe Johns Hopkins Clinical Research Scholars Program is now seeking applications for the 2021-22 KL2 Mentored Career Development Awards. We anticipate being able to offer up to four awards with appointments beginning between July 1, 2021 and November 1, 2021. Applicants must be junior faculty members or have a pending promotion to faculty status prior […]
Parenting and Caregiving during Covid: for School of Medicine Faculty and Staff
Posted by | LeadershipHear from Johns Hopkins experts in education, mental health and medicine about the latest recommendations, resources and guidance. Speakers include: Karen Swartz, MD, Associate Professor of Psychiatry Carisa Parrish, PhD, Associate Professor of Psychiatry Annette Anderson, PhD, Assistant Professor of Education Heidi Conway, Vice President for Human Resources Thursday October 8, from 4-5 p.m. Click […]
Trends in Internal Medicine Faculty by Sex and Race/Ethnicity, 1980-2018
Posted by | Article of the WeekARTICLE: Trends in Internal Medicine Faculty by Sex and Race/Ethnicity, 1980-2018 AUTHORS: S. Michelle Ogunwole, Michael Dill, Karen Jones, Sherita H. Golden JOURNAL: JAMA Netw Open. 2020 Sep 1;3(9):e2015205. doi: 10.1001/jamanetworkopen.2020.15205. Abstract Importance: Increasing diversity in the physician workforce is a fulcrum for reducing health disparities. Efforts to increase the diversity in the internal medicine (IM) […]