Medicine Matters

Sharing successes, challenges and daily happenings in the Department of Medicine

AOTW

A Transatlantic Comparison of Patient-Reported Access to and Use of Aspirin in Contemporary Preventive Cardiology

March 16, 2022

ARTICLE: A Transatlantic Comparison of Patient-Reported Access to and Use of Aspirin in Contemporary Preventive Cardiology AUTHORS: Alan P Jacobsen, Zi Lun Lim, Blair Chang, Kaleb D Lambeth, Thomas M Das, Colin Gorry, Michael McCague, William Wijns, Patrick W J C Serruys, Roger S Blumenthal, Seth S Martin, John W McEvoy JOURNAL: J Am Coll Cardiol. 2021 Sep 14;78(11):1193-1195. doi: 10.1016/j.jacc.2021.07.015. Aspirin is effective in the secondary prevention […]

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CD4+ T cells from COVID-19 mRNA vaccine recipients recognize a conserved epitope present in diverse coronaviruses

March 16, 2022

ARTICLE: CD4+ T cells from COVID-19 mRNA vaccine recipients recognize a conserved epitope present in diverse coronaviruses AUTHORS: Bezawit A Woldemeskel, Arbor G Dykema, Caroline C Garliss, Saphira Cherfils, Kellie N Smith, Joel N Blankson JOURNAL: J Clin Invest. 2022 Mar 1;132(5):e156083. doi: 10.1172/JCI156083. Abstract Recent studies have shown that vaccinated individuals harbor T cells that can cross-recognize SARS-CoV-2 and endemic human […]

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Gender Differences in Medicare Payments Among Cardiologists

March 9, 2022

ARTICLE: Gender Differences in Medicare Payments Among Cardiologists AUTHORS: Inbar Raber, Mahmoud Al Rifai, Cian P. McCarthy, Muthiah Vaduganathan, Erin D. Michos, Malissa J. Wood, Yvonne M. Smyth, Nasrien E. Ibrahim, Aarti Asnani, Roxana Mehran, John W. McEvoy JOURNAL: JAMA Cardiol. 2021 Dec 1;6(12):1432-1439. doi: 10.1001/jamacardio.2021.3385. Abstract Importance: Women cardiologists receive lower salaries than men; however, it is […]

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Mitochondrial Creatine Kinase Attenuates Pathologic Remodeling in Heart Failure

March 9, 2022

ARTICLE: Mitochondrial Creatine Kinase Attenuates Pathologic Remodeling in Heart Failure AUTHORS: Gizem Keceli, Ashish Gupta, Joevin Sourdon, Refaat Gabr, Michael Schär, Swati Dey, Carlo G Tocchetti, Annina Stuber, Jacopo Agrimi, Yi Zhang, Michelle Leppo, Charles Steenbergen, Shenghan Lai, Lisa R Yanek, Brian O'Rourke, Gary Gerstenblith, Paul A Bottomley, Yibin Wang, Nazareno Paolocci, Robert G Weiss JOURNAL: Circ Res. 2022 Mar 4;130(5):741-759. doi: 10.1161/CIRCRESAHA.121.319648. Epub 2022 Feb 3. Abstract Background: Abnormalities in cardiac energy metabolism occur in heart failure […]

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Understanding Patients’ Perceived Health After Critical Illness: Analysis of Two Prospective, Longitudinal Studies of ARDS Survivors

March 2, 2022

ARTICLE: Understanding Patients’ Perceived Health After Critical Illness: Analysis of Two Prospective, Longitudinal Studies of ARDS Survivors AUTHORS: Alison E Turnbull, Hongkai Ji, Victor D Dinglas, Albert W Wu, Pedro A Mendez-Tellez, Cheryl Dennison Himmelfarb, Carl B Shanholtz, Megan M Hosey, Ramona O Hopkins, Dale M Needham JOURNAL: Chest. 2022 Feb;161(2):407-417. doi: 10.1016/j.chest.2021.07.2177. Epub 2021 Aug 19. Abstract Background: Perceived health is one of the strongest determinants of […]

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Evaluation of Representation of Women as Authors in Pivotal Trials Supporting US Food and Drug Administration Approval of Novel Cardiovascular Drugs

March 2, 2022

ARTICLE: Evaluation of Representation of Women as Authors in Pivotal Trials Supporting US Food and Drug Administration Approval of Novel Cardiovascular Drugs AUTHORS: Izza Shahid, Muhammad Shahzeb Khan, Aruba Sohail, Safi U Khan, Stephen J Greene, Marat Fudim, Erin D Michos JOURNAL: JAMA Netw Open. 2022 Feb 1;5(2):e220035. doi: 10.1001/jamanetworkopen.2022.0035. Abstract Introduction: Pivotal efficacy trials provide foundational evidence supporting US Food and […]

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Sex Differences in Health Status and Clinical Outcomes After Nonprimary Percutaneous Coronary Intervention

February 23, 2022

ARTICLE: Sex Differences in Health Status and Clinical Outcomes After Nonprimary Percutaneous Coronary Intervention AUTHORS: Pranoti G Hiremath, Thomas Aversano, John A Spertus, Cynthia C Lemmon, Daniel Q Naiman, Matthew J Czarny JOURNAL: Circ Cardiovasc Interv. 2022 Feb;15(2):e011308. doi: 10.1161/CIRCINTERVENTIONS.121.011308. Epub 2022 Jan 23. Abstract Background: Greater insight into sex-based differences in health status can lay the foundation for more equitable health care. This […]

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Diastolic Dysfunction in Systemic Sclerosis: Risk Factors and Impact on Mortality

February 16, 2022

ARTICLE: Diastolic Dysfunction in Systemic Sclerosis: Risk Factors and Impact on Mortality AUTHORS: Alicia M Hinze, Jamie Perin, Adrianne Woods, Laura K Hummers, Fredrick M Wigley, Monica Mukherjee, Ami A Shah JOURNAL: Arthritis Rheumatol. 2021 Dec 20. doi: 10.1002/art.42054. Online ahead of print. Abstract Objective: To determine the independent risk factors for diastolic dysfunction (DD) in patients with systemic sclerosis (SSc) and to evaluate the […]

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The Effect of Buprenorphine on Human Immunodeficiency Virus Viral Suppression

February 9, 2022

ARTICLE: The Effect of Buprenorphine on Human Immunodeficiency Virus Viral Suppression AUTHORS: Jongyeon Kim, Catherine R Lesko, Anthony T Fojo, Jeanne C Keruly, Richard D Moore, Geetanjali Chander, Bryan Lau  JOURNAL: Clin Infect Dis. 2021 Dec 6;73(11):1951-1956. doi: 10.1093/cid/ciab578.  Abstract Background: Opioid use is prevalent among people living with human immunodeficiency virus (HIV; PLWH) and adversely affects HIV outcomes. We assessed the effect of […]

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Factors Associated With Overuse of Health Care Within US Health System

February 9, 2022

ARTICLE: Factors Associated With Overuse of Health Care Within US Health System AUTHORS: Jodi B. Segal, Aditi P. Sen, Eliana Glanzberg-Krainin, Susan Hutfless JOURNAL: JAMA Health Forum. 2022;3(1):e214543. doi:10.1001/jamahealthforum.2021.4543 Abstract Importance: Overuse of health care is a pervasive threat to patients that requires measurement to inform the development of interventions. Objective: To measure low-value health care use […]

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About the Director

Mark Anderson, M.D., Ph.D - William Osler Professor of Medicine, director of the Department of Medicine in the Johns Hopkins University School of Medicine

Mark Anderson, M.D., Ph.D is the William Osler Professor of Medicine, director of the Department of Medicine in the Johns Hopkins University School of Medicine and physician-in-chief of The Johns Hopkins Hospital... read more »

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Medicine Matters is a place to share department news in a way that is accessible to all and discuss issues and challenges important to our faculty, staff and academic medicine overall... read more »

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