Medicine Matters

ARTICLE: A Transatlantic Comparison of Patient-Reported Access to and Use of Aspirin in Contemporary Preventive Cardiology AUTHORS: Alan P Jacobsen, Zi Lun Lim, Blair Chang, Kaleb D Lambeth, Thomas M Das, Colin Gorry, Michael McCague, William Wijns, Patrick W J C Serruys, Roger S Blumenthal, Seth S Martin, John W McEvoy JOURNAL: J Am Coll Cardiol. 2021 Sep 14;78(11):1193-1195. doi: 10.1016/j.jacc.2021.07.015. Aspirin is effective in the secondary prevention […]

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ARTICLE: CD4+ T cells from COVID-19 mRNA vaccine recipients recognize a conserved epitope present in diverse coronaviruses AUTHORS: Bezawit A Woldemeskel, Arbor G Dykema, Caroline C Garliss, Saphira Cherfils, Kellie N Smith, Joel N Blankson JOURNAL: J Clin Invest. 2022 Mar 1;132(5):e156083. doi: 10.1172/JCI156083. Abstract Recent studies have shown that vaccinated individuals harbor T cells that can cross-recognize SARS-CoV-2 and endemic human […]

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ARTICLE: Gender Differences in Medicare Payments Among Cardiologists AUTHORS: Inbar Raber, Mahmoud Al Rifai, Cian P. McCarthy, Muthiah Vaduganathan, Erin D. Michos, Malissa J. Wood, Yvonne M. Smyth, Nasrien E. Ibrahim, Aarti Asnani, Roxana Mehran, John W. McEvoy JOURNAL: JAMA Cardiol. 2021 Dec 1;6(12):1432-1439. doi: 10.1001/jamacardio.2021.3385. Abstract Importance: Women cardiologists receive lower salaries than men; however, it is […]

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ARTICLE: Mitochondrial Creatine Kinase Attenuates Pathologic Remodeling in Heart Failure AUTHORS: Gizem Keceli, Ashish Gupta, Joevin Sourdon, Refaat Gabr, Michael Schär, Swati Dey, Carlo G Tocchetti, Annina Stuber, Jacopo Agrimi, Yi Zhang, Michelle Leppo, Charles Steenbergen, Shenghan Lai, Lisa R Yanek, Brian O'Rourke, Gary Gerstenblith, Paul A Bottomley, Yibin Wang, Nazareno Paolocci, Robert G Weiss JOURNAL: Circ Res. 2022 Mar 4;130(5):741-759. doi: 10.1161/CIRCRESAHA.121.319648. Epub 2022 Feb 3. Abstract Background: Abnormalities in cardiac energy metabolism occur in heart failure […]

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ARTICLE: Understanding Patients’ Perceived Health After Critical Illness: Analysis of Two Prospective, Longitudinal Studies of ARDS Survivors AUTHORS: Alison E Turnbull, Hongkai Ji, Victor D Dinglas, Albert W Wu, Pedro A Mendez-Tellez, Cheryl Dennison Himmelfarb, Carl B Shanholtz, Megan M Hosey, Ramona O Hopkins, Dale M Needham JOURNAL: Chest. 2022 Feb;161(2):407-417. doi: 10.1016/j.chest.2021.07.2177. Epub 2021 Aug 19. Abstract Background: Perceived health is one of the strongest determinants of […]

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ARTICLE: Evaluation of Representation of Women as Authors in Pivotal Trials Supporting US Food and Drug Administration Approval of Novel Cardiovascular Drugs AUTHORS: Izza Shahid, Muhammad Shahzeb Khan, Aruba Sohail, Safi U Khan, Stephen J Greene, Marat Fudim, Erin D Michos JOURNAL: JAMA Netw Open. 2022 Feb 1;5(2):e220035. doi: 10.1001/jamanetworkopen.2022.0035. Abstract Introduction: Pivotal efficacy trials provide foundational evidence supporting US Food and […]

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ARTICLE: Sex Differences in Health Status and Clinical Outcomes After Nonprimary Percutaneous Coronary Intervention AUTHORS: Pranoti G Hiremath, Thomas Aversano, John A Spertus, Cynthia C Lemmon, Daniel Q Naiman, Matthew J Czarny JOURNAL: Circ Cardiovasc Interv. 2022 Feb;15(2):e011308. doi: 10.1161/CIRCINTERVENTIONS.121.011308. Epub 2022 Jan 23. Abstract Background: Greater insight into sex-based differences in health status can lay the foundation for more equitable health care. This […]

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ARTICLE: Diastolic Dysfunction in Systemic Sclerosis: Risk Factors and Impact on Mortality AUTHORS: Alicia M Hinze, Jamie Perin, Adrianne Woods, Laura K Hummers, Fredrick M Wigley, Monica Mukherjee, Ami A Shah JOURNAL: Arthritis Rheumatol. 2021 Dec 20. doi: 10.1002/art.42054. Online ahead of print. Abstract Objective: To determine the independent risk factors for diastolic dysfunction (DD) in patients with systemic sclerosis (SSc) and to evaluate the […]

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ARTICLE: The Effect of Buprenorphine on Human Immunodeficiency Virus Viral Suppression AUTHORS: Jongyeon Kim, Catherine R Lesko, Anthony T Fojo, Jeanne C Keruly, Richard D Moore, Geetanjali Chander, Bryan Lau  JOURNAL: Clin Infect Dis. 2021 Dec 6;73(11):1951-1956. doi: 10.1093/cid/ciab578.  Abstract Background: Opioid use is prevalent among people living with human immunodeficiency virus (HIV; PLWH) and adversely affects HIV outcomes. We assessed the effect of […]

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ARTICLE: Factors Associated With Overuse of Health Care Within US Health System AUTHORS: Jodi B. Segal, Aditi P. Sen, Eliana Glanzberg-Krainin, Susan Hutfless JOURNAL: JAMA Health Forum. 2022;3(1):e214543. doi:10.1001/jamahealthforum.2021.4543 Abstract Importance: Overuse of health care is a pervasive threat to patients that requires measurement to inform the development of interventions. Objective: To measure low-value health care use […]

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