Article of the Week

Looking Beyond the Tip of a Tusk: Balancing the Evidence in Prognosis-related Communication

Looking Beyond the Tip of a Tusk: Balancing the Evidence in Prognosis-related Communication

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ARTICLE: Looking Beyond the Tip of a Tusk: Balancing the Evidence in Prognosis-related Communication. AUTHORS: Rebecca A Aslakson and Mary Catherine Beach JOURNAL: Am J Respir Crit Care Med. 2017 May 16. doi: 10.1164/rccm.201704-0851ED. [Epub ahead of print] Evidence supports a poor prognosis for patients with chronic critical illness; 30- 40% die prior to hospital discharge, and another(...)

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A microbiome variable in the HIV-prevention equation

A microbiome variable in the HIV-prevention equation

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ARTICLE: A microbiome variable in the HIV-prevention equation AUTHORS: Susan Tuddenham and Khalil G. Ghanem JOURNAL: Science. 2017 Jun 2;356(6341):907-908. doi: 10.1126/science.aan6103. Summary The healthy vaginal microbiota is typically characterized by the predominance of Lactobacillus species (including L. crispatus, L. jensenii, L. gasseri, and L. iners). These bacteria are thought to protect against pathogens through a variety of mechanisms, including(...)

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Oral Direct-Acting Agent Therapy for Hepatitis C Virus Infection: A Systematic Review

Oral Direct-Acting Agent Therapy for Hepatitis C Virus Infection: A Systematic Review

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ARTICLE: Oral Direct-Acting Agent Therapy for Hepatitis C Virus Infection: A Systematic Review AUTHORS: Oluwaseun Falade-Nwulia, Catalina Suarez-Cuervo, David R. Nelson, Michael W. Fried, Jodi B. Segal, Mark S. Sulkowski JOURNAL: Ann Intern Med. 2017 May 2;166(9):637-648. doi: 10.7326/M16-2575. Epub 2017 Mar 21. Abstract BACKGROUND: Rapid improvements in hepatitis C virus (HCV) therapy have led to(...)

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Emergency Department Query for Patient-Centered Approaches to Sexual Orientation and Gender Identity: The EQUALITY Study

Emergency Department Query for Patient-Centered Approaches to Sexual Orientation and Gender Identity: The EQUALITY Study

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ARTICLE: Emergency Department Query for Patient-Centered Approaches to Sexual Orientation and Gender Identity: The EQUALITY Study AUTHORS: Adil H. Haider, Eric B. Schneider, Lisa M. Kodadek, Rachel R. Adler, Anju Ranjit, Maya Torain, Ryan Y. Shields, Claire Snyder, Jeremiah D. Schuur, Laura Vail, Danielle German, Susan Peterson, Brandyn D. Lau JOURNAL: JAMA Intern Med. 2017 Jun 1;177(6):819-828. doi: 10.1001/jamainternmed.2017.0906. Abstract IMPORTANCE: The Institute of Medicine and The Joint Commission recommend routine documentation of patients'(...)

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A Year at the Bedside With Osler

A Year at the Bedside With Osler

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ARTICLE: A Year at the Bedside With Osler AUTHORS: Jason Liebowitz JOURNAL: JAMA Intern Med. 2017 May 1. doi: 10.1001/jamainternmed.2017.1080. [Epub ahead of print] He who studies medicine without books sails an uncharted sea, but he who studies medicine without patients does not go to sea at all. Sir William Osler1 Ask any resident, and he or(...)

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Benefits and Harms of Osteoporosis Medications in Patients With Chronic Kidney Disease: A Systematic Review and Meta-analysis

Benefits and Harms of Osteoporosis Medications in Patients With Chronic Kidney Disease: A Systematic Review and Meta-analysis

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ARTICLE: Benefits and Harms of Osteoporosis Medications in Patients With Chronic Kidney Disease: A Systematic Review and Meta-analysis. AUTHORS: Lisa M. Wilson, Casey M. Rebholz, Ermias Jirru, Marisa Chi Liu, Allen Zhang, Jessica Gayleard, Karen A. Robinson JOURNAL: Ann Intern Med. 2017 May 2;166(9):649-658. doi: 10.7326/M16-2752. Epub 2017 Apr 11. Abstract BACKGROUND: Complications of chronic kidney(...)

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Physician Breast Cancer Screening Recommendations Following Guideline Changes: Results of a National Survey

Physician Breast Cancer Screening Recommendations Following Guideline Changes: Results of a National Survey

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ARTICLE: Physician Breast Cancer Screening Recommendations Following Guideline Changes: Results of a National Survey AUTHORS: Archana Radhakrishnan, Sarah A. Nowak, Andrew M. Parker, Kala Visvanathan, Craig Evan Pollack JOURNAL: JAMA Intern Med. 2017 Apr 10. doi: 10.1001/jamainternmed.2017.0453. [Epub ahead of print] Different professional societies and organizations continue to disagree over the optimal time to initiate and discontinue breast cancer screening mammography and the(...)

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Cardiometabolic Abnormalities Among Normal-Weight Persons From Five Racial/Ethnic Groups in the United States: A Cross-sectional Analysis of Two Cohort Studies

Cardiometabolic Abnormalities Among Normal-Weight Persons From Five Racial/Ethnic Groups in the United States: A Cross-sectional Analysis of Two Cohort Studies

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ARTICLE: Cardiometabolic Abnormalities Among Normal-Weight Persons From Five Racial/Ethnic Groups in the United States: A Cross-sectional Analysis of Two Cohort Studies. AUTHORS: Unjali P. Gujral, Eric Vittinghoff, Morgana Mongraw-Chaffin, Dhananjay Vaidya, Namratha R. Kandula, Matthew Allison, Jeffrey Carr, Kiang Liu, K.M. Venkat Narayan, Alka M. Kanaya JOURNAL: Ann Intern Med. 2017 May 2;166(9):628-636. doi: 10.7326/M16-1895. Epub(...)

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Resident Duty Hours and Medical Education Policy — Raising the Evidence Bar

Resident Duty Hours and Medical Education Policy — Raising the Evidence Bar

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ARTICLE: Resident Duty Hours and Medical Education Policy — Raising the Evidence Bar AUTHORS: David A. Asch, Karl Y. Bilimoria and Sanjay V. Desai JOURNAL: N Engl J Med. 2017 Apr 5. doi: 10.1056/NEJMp1703690. [Epub ahead of print] On March 10, 2017, the Accreditation Council for Graduate Medical Education (ACGME) issued revised common program requirements for(...)

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Uninterrupted Dabigatran versus Warfarin for Ablation in Atrial Fibrillation

Uninterrupted Dabigatran versus Warfarin for Ablation in Atrial Fibrillation

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ARTICLE: Uninterrupted Dabigatran versus Warfarin for Ablation in Atrial Fibrillation AUTHORS: Hugh Calkins, Stephan Willems, Edward P. Gerstenfeld, Atul Verma, Richard Schilling, Stefan H. Hohnloser, Ken Okumura, Harvey Serota, Matias Nordaby, Kelly Guiver, Branislav Biss, Marc A. Brouwer and Massimo Grimaldi JOURNAL: N Engl J Med. 2017 Mar 19. doi: 10.1056/NEJMoa1701005. [Epub ahead of print] Abstract(...)

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